Brand names for fentanyl patches include Duragesic, Matrifen, and Tilofyl. Each patch lasts for approximately 72 hours. Transdermal patches deliver constant, potent opioid medication that is absorbed via the skin. The patches come in four different, transparent sizes beginning at 2. The largest application is about four square inches.
Transdermal fentanyl patches include four layers that regulate the delivery of fentanyl in a complex mechanism. Fentanyl patches are a sort-of last resort pain management system after other approaches have not worked. They are only prescribed if someone is already opioid-dependent as a result of taking at least 60 mg of morphine, 30 mg of oxycodone, or 8 mg of hydromorphone daily. The risk of a fentanyl overdose is significantly higher for someone who is not already opioid-dependent.
Fentanyl patches are only prescribed to a particular patient who needs relief from moderate to severe, persistent pain that other methods have proven to be ineffective. Some of the side effects of fentanyl patches can range from mild to severe. These symptoms include:. The delivery system can feel like it is burning skin. Other people report intense nausea and vomiting due to the high potency of the drug. Sleepiness seems like a mild side effect; however, it can be an indicator that the dose of fentanyl is too high.
If too much of this medicine is used for a long time, it may become habit-forming causing mental or physical dependence or cause an overdose. The fentanyl skin patch is only used for opioid-tolerant patients. A patient is opioid-tolerant if oral narcotics have already been used for severe pain. Check with your doctor if you have questions about this. It is very important that you understand the rules of the Opioid Analgesic REMS program to prevent addiction, abuse, and misuse of fentanyl.
This medicine should also come with a Medication Guide and patient instructions. Read and follow these instructions carefully. Read it again each time you refill your prescription in case there is new information.
Ask your doctor if you have any questions. A nurse or other trained health professional will give you this medicine after surgery. You will be taught how to use this medicine in the hospital, but the patch will be removed by your healthcare provider before you leave the hospital.
Do not leave the hospital with the patch on your skin. A certain amount of the medicine must build up in the skin before it is absorbed into the body. Up to a full day 24 hours may pass before the first dose begins to work. Your doctor may need to adjust the dose during the first few weeks before finding the amount that works best for you. Even if you feel that the medicine is not working, do not increase the amount of fentanyl skin patch that you apply. Instead, check first with your doctor.
You will probably need to take a faster-acting narcotic by mouth to relieve pain during the first few days of using fentanyl skin patch.
You may also need another narcotic while your dose of fentanyl is being adjusted, and to relieve any "breakthrough" pain that occurs later on. Be sure you do not take more of the other narcotic, and do not take it more often than directed. Taking 2 narcotics together can increase the chance of serious side effects. Grapefruit and grapefruit juice may increase the effects of fentanyl skin patch by increasing the amount of the medicine in your body.
You should not consume grapefruit products while you are using this medicine. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:. Other side effects not listed may also occur in some patients.
If you notice any other effects, check with your healthcare professional. Call your doctor for medical advice about side effects.
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